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Lead poisoning occurs
when you absorb too much lead by breathing or swallowing a substance with lead
in it, such as paint, dust, water, or food. Lead can damage almost every organ system.
In children, too much lead in the body can cause
lasting problems with growth and development. These can affect behavior, hearing, and learning and can slow the child's growth.
In adults, lead poisoning can damage the brain and nervous system, the stomach, and the kidneys. It can also cause high blood pressure and other health problems.
Although it isn't normal to have lead in your body, a small amount is
present in most people. Environmental laws have reduced lead exposure in the
United States, but it is still a health risk, especially for young
Lead poisoning is
usually caused by months or years of exposure to small amounts of lead at home,
work, or day care. It can also happen very quickly with exposure to a large amount of lead. Many things can contain or be contaminated with lead: paint, air, water, soil, food, and manufactured goods.
The most common source of lead exposure for children is
lead-based paint and the dust and soil that are
contaminated by it. This can be a problem in older homes and buildings.
most often exposed to lead at work or while doing hobbies that involve lead.
poisoning can occur at any age, but children are most likely to be affected by high lead levels. Children at highest risk include
Others at risk for lead poisoning include people who:
You may not notice any symptoms at first. The effects are easy to miss and may seem related to other
conditions. The higher the amount of lead in the body, the more severe the symptoms are.
In children, symptoms can include:
lead poisoning can cause:
Severe cases can cause seizures, paralysis, and coma.
The doctor will ask questions and do a physical exam to look for signs of lead poisoning. If your doctor suspects lead poisoning, he or she will do a blood test to find out the amount of lead in the
Diagnosing lead poisoning is difficult, because the
symptoms can be caused by many diseases. Most children with lead poisoning don't have symptoms until their blood lead levels are very high.
In the United States, there are screening programs to check lead levels in children who are likely to be exposed to lead. Whether your child needs to be tested depends in part on where you live, how old your housing is, and other risk factors. Talk to your
child's doctor about whether your child is at risk and should be screened.
Adults usually aren't screened for lead poisoning unless they have a job that involves working with lead. For these workers, companies usually are required to provide testing.
If you are pregnant or trying to get pregnant and have a family
member who works with lead, you may want to ask your doctor about your risk for
lead poisoning. But in general, experts don't recommend routine testing for lead in pregnant women who don't have symptoms.2
Treatment for lead poisoning includes removing the source of lead, getting good nutrition, and, in some cases, having chelation therapy.
Removing the source of lead. Old paint chips and dirt are the most common sources of lead in the home. Lead-based paint, and the dirt and dust that come along with it, should be removed by professionals. In the workplace, removal usually means removing lead dust that's in the air and making sure that people don't bring contaminated dust or dirt on their clothing into their homes or other places.
Good nutrition. Eating foods that have enough iron and other vitamins and minerals may be enough to reduce lead levels in the
body. A person who eats a balanced, nutritious diet may absorb less lead than someone with a poor diet.
Chelation therapy. If removing the lead source and getting good nutrition don't work, or if lead levels are very high,
you may need to take chelating medicines. These medicines bind to lead in the body and help remove it.
If blood lead levels don't come down with treatment, home and work areas may need to be rechecked. Call your local health department to see what inspection services are offered in your area.
The best way to avoid lead poisoning is to prevent it. Treatment cannot reverse any damage that has already occurred. But there are many ways to reduce your exposure—and your child's—before it causes symptoms.
Learning about lead poisoning:
The latest information on childhood lead poisoning is
available on this Web site.
This website is sponsored by the Nemours Foundation. It
has a wide range of information about children's health—from allergies and
diseases to normal growth and development (birth to adolescence). This website
offers separate areas for kids, teens, and parents, each providing
age-appropriate information that the child or parent can understand. You can
sign up to get weekly emails about your area of interest.
The ToxTown website gives you information about toxic
chemicals and environmental health risks that you might encounter in everyday
life. It provides facts on everyday places where toxic chemicals may be found,
and it gives information about how the environment can affect health. ToxTown
includes common environmental hazards in towns, cities, farms, and U.S.-Mexico
border communities. The site is interactive and very user-friendly. You click
on simple graphics to be directed to specific information that you are
interested in learning about.
The Occupational Safety and Health Administration (OSHA)
provides information about hazards at the workplace and about worker
The Consumer Product Safety Commission (CPSC) is an
independent federal regulatory agency. CPSC seeks to protect consumers and families from dangerous products that can injure people, especially children. CPSC develops safety standards and informs the public about product hazards and recalls. You can call
their toll-free number or email them to report unsafe products.
From this Web site, you can get information about lead
poisoning, lead exposure, local resources, and lead testing. You can also link
to National Lead Information Center information about lead hazards and their
Committee on Environmental Health, American Academy of Pediatrics (2005, reaffirmed 2009). Lead exposure in children: Prevention, detection, and management. Pediatrics, 116: 1036–1046. Also available online: http://www.pediatrics.org/cgi/content/full/116/4/1036.
U.S. Preventive Services Task Force (2006). Screening for elevated blood lead levels in children and pregnant women. Available online: http://www.uspreventiveservicestaskforce.org/uspstf/uspslead.htm.
Other Works Consulted
Binns HJ, et al. (2007). Interpreting and managing blood lead levels of less than 10 mcg/dL in children and reducing childhood exposure to lead: Recommendations of the Centers for Disease Control and Prevention Advisory Committee on Childhood Lead Poisoning Prevention. Pediatrics, 120(5): e1285–e1298.
Centers for Disease Control and Prevention (2002). Managing elevated blood lead levels among young children: Recommendations from the Advisory Committee on Childhood Lead Poisoning Prevention. Available online: http://www.cdc.gov/nceh/lead/CaseManagement/caseManage_main.htm.
Centers for Disease Control and Prevention (2005). Preventing
lead poisoning in young children. Available online:
Centers for Disease Control and Prevention (2012). Lead in drinking water and human blood lead levels in the United States. MMWR, 61(Supplement): 1–9. Also available online:
Grandjean P (2008). Lead section of Health significance of metal
exposures. In RB Wallace, ed., Wallace/Maxcy-Rosenau-Last Public Health and
Preventive Medicine, 15th ed., pp. 609–611. New York: McGraw-Hill.
Henretig FM (2009). Lead section of Toxins. In WB Carey et al., eds., Developmental-Behavioral Pediatrics, 4th ed., pp. 319–321. Philadelphia: Saunders Elsevier.
Long H, Nelson LS (2011). Metals and metalloids. In JE Tintinalli, ed., Tintinalli's Emergency Medicine: A Comprehensive Study Guide, 7th ed., pp. 1308–1315. New York: McGraw-Hill.
Markowitz M (2011). Lead poisoning. In RM Kliegman et al., eds., Nelson Textbook of Pediatrics, 19th ed., pp. 2448–2453. Philadelphia: Saunders.
Mcguigan MA (2012). Chronic poisoning: Trace metals and others. In L Goldman, A Shafer, eds., Goldman's Cecil Medicine, 24th ed., pp. 88–95. Philadelphia: Saunders.
Olsen KR (2012). Poisoning. In SJ McPhee, MA Papadakis, eds., 2012 Current Medical Diagnosis and Treatment, 51st ed., pp. 1518–1547. New York: McGraw-Hill Medical.
Shannon MW (2007). Lead. In MW Shannon et al., eds., Haddad and Winchester's Clinical Management of Poisoning and Drug Overdose, 4th ed., pp. 1129–1146. Philadelphia: Saunders Elsevier.
U.S. Centers for Disease Control (2005). Blood lead levels—United States, 1999–2002. MMWR, 54(20): 513–516. Also available online:
Woolf AD, et al. (2007). Update on the clinical management of childhood lead poisoning. Pediatric Clinics of North America, 54(2): 271–294.
Woolfenden YB, et al. (2008). Household interventions for prevention of domestic lead exposure in children. Cochrane Database of Systematic Reviews (2).
June 5, 2012
John Pope, MD - Pediatrics & R. Steven Tharratt, MD, MPVM, FACP, FCCP - Pulmonology, Critical Care Medicine, Medical Toxicology
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